Brown is out with a bruised left shoulder. Jackson missed the previous two games with a right knee injury, and Ugoh was a healthy scratch. Pro Bowl receiver Reggie Wayne is active and expected to start.

Also out for the Colts are kicker Adam Vinatieri, return specialist T.J. Rushing and guard Jamey Richard.

Inactives for San Francisco are receivers Micheal Spurlock and Jason Hill, safety Reggie Smith, linebacker Diyral Briggs, offensive linemen Cody Wallace and Chris Patrick, and defensive tackle Ricky Jean Francois.

(Copyright 2009 by The Associated Press. All Rights Reserved.)